Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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391
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405
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391
Tocris Bioscience™ Thalidomide-4-hydroxyacetate
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Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs
392
Tocris Bioscience™ EPPTB
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Trace amine 1 (TA1) receptor antagonist/inverse agonist
| Target | Trace Amine 1 (TA1) Receptor Antagonists |
|---|---|
| CAS | 1110781-88-8 |
| Purity | >99% |
| Chemical Name or Material | N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C20H21F3N2O2 |
| Formula Weight | 378.39 |
393
Tocris Bioscience™ XAC
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CAS: 1962928-23-9 Molecular Formula: C21H30Cl2N6O4
| CAS | 1962928-23-9 |
|---|---|
| Molecular Formula | C21H30Cl2N6O4 |
394
Tocris Bioscience™ AMZ 30
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Potent, selective and irreversible protein phosphatase methylesterase-1 (PME-1) inhibitor
| Target | Hydrolase Inhibitors |
|---|---|
| CAS | 1313613-09-0 |
| Purity | 0.98 |
| Chemical Name or Material | (2 E)-2-[(4-Fluorophenyl)sulfonyl]-3-[1-[(3-nitrophenyl)sulfonyl]-1 H-pyrrol-2-yl]-2-propenenitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H12FN3O6S2 |
395
Tocris Bioscience™ (S)-(-)-Carbidopa
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CAS: 28860-95-9 Molecular Formula: C10H14N2O4
| CAS | 28860-95-9 |
|---|---|
| Molecular Formula | C10H14N2O4 |
396
Tocris Bioscience™ Gavestinel
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CAS: 153436-38-5 Molecular Formula: C18H12Cl2N2NaO3
| CAS | 153436-38-5 |
|---|---|
| Molecular Formula | C18H12Cl2N2NaO3 |
397
Tocris Bioscience™ Thalidomide 4'-ether-PEG3-amine
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Cereblon ligand with PEG linker and terminal amine for onward chemistry
398
Tocris Bioscience™ Marimastat
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 154039-60-8 Molecular Formula: C15H29N3O5
| CAS | 154039-60-8 |
|---|---|
| Molecular Formula | C15H29N3O5 |
399
Tocris Bioscience™ NGB 2904
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 189061-11-8 Molecular Formula: C28H30Cl3N3O
| CAS | 189061-11-8 |
|---|---|
| Molecular Formula | C28H30Cl3N3O |
400
Tocris Bioscience™ GSK 2018682
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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S1P1 and S1P5 agonist
| Product Type | Agonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H21ClN4O4 |
| Formula Weight | 440.88 |
401
Tocris Bioscience™ ML 218 hydrochloride
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CAS: 2319922-08-0 Molecular Formula: C19H27Cl3N2O
| CAS | 2319922-08-0 |
|---|---|
| Molecular Formula | C19H27Cl3N2O |
402
Tocris Bioscience™ SB 222200
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 174635-69-9 Molecular Formula: C26H24N2O
| CAS | 174635-69-9 |
|---|---|
| Molecular Formula | C26H24N2O |
403
Tocris Bioscience™ RN 9893 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective TRPV4 antagonist
| Target | TRPV Antagonists |
|---|---|
| CAS | 2109450-40-8 |
| Purity | >99% |
| Chemical Name or Material | N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C21H23F3N4O5S.HCl |
| Formula Weight | 536.95 |
404
Tocris Bioscience™ T4
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Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3
| Target | DNA, RNA and Protein Synthesis Compounds |
|---|---|
| CAS | 785708-33-0 |
| Purity | 0.98 |
| Chemical Name or Material | 6,7-Dimethoxy-2-[((4-phenyl-3,6-dihydropyridin-1(2 H)-yl)methyl)]quinazolin-4(3 H)-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H23N3O3 |
405
| Shipping Condition | No special requirements |
|---|---|
| CAS | 1441674-54-9 |
| Color | White to Yellow |
| Purity | ≥97.5% |
| Physical Form | Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | Ledipasvir acetone |
| Recommended Storage | Normal conditions |
| Molecular Formula | C49 H54 F2 N8 O6 . C3 H6 O |
| Product Line | Life science |