Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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391
Tocris Bioscience™ BAY 091
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective PIP4K2A inhibitor
| Target | Other Kinase Inhibitors |
|---|---|
| CAS | 2922280-34-8 |
| Purity | 0.98 |
| Chemical Name or Material | (R)-2-((3-Cyano-2-(2 '-fluoro-3 '-methyl-[1,1 '-biphenyl]-4-yl)-1,7-naphthyridin-4-yl)amino)butanoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H21FN4O2 |
392
| Shipping Condition | No special requirements |
|---|---|
| CAS | 826-39-1 |
| Color | White to Almost-white |
| Purity | ≥97.5% |
| Physical Form | Powder |
| Health Hazard 1 | Skull and crossbones |
| Chemical Name or Material | Mecamylamine hydrochloride |
| Recommended Storage | Refrigerator +4°C |
| Synonym | 2-(Methylamino)isocamphane hydrochloride |
| Molecular Formula | C11 H21 N . H Cl |
| EINECS Number | 212-555-8 |
| Melting Point | >240°C (D) |
| Product Line | Life science |
393
Thermo Scientific Chemicals Azasetron hydrochloride
CAS: 123040-16-4 Molecular Formula: C17H21Cl2N3O3
| CAS | 123040-16-4 |
|---|---|
| Molecular Formula | C17H21Cl2N3O3 |
395
| CAS | 519-02-8 |
|---|---|
| Molecular Formula | C15H24N2O |
396
| Target | Histone Demethylase Inhibitors |
|---|---|
| CAS | 861224-48-8 |
| Purity | 0.98 |
| Chemical Name or Material | 8-Benzoyl-2,3,6,7-tetrahydro-5-oxo-5H-thiazolo[3,2-a]pyridine-6-acetic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H15NO4S |
397
Tocris Bioscience™ cis-22a
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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TRPV6 inhibitor
| Target | TRPV Inhibitors |
|---|---|
| CAS | 1819366-84-1 |
| Purity | 0.98 |
| Chemical Name or Material | 1-[cis-4-(3-Methylphenyl)cyclohexyl]-4-(3-pyridinyl)piperazine ditrifluoroacetate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H29N30.2 CF3CO2H |
398
Tocris Bioscience™ T3 CLK
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B
| Target | Cdc2-like Kinase Inhibitors |
|---|---|
| CAS | 2109805-56-1 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H30N6O2 |
399
Tocris Bioscience™ MO-I-500
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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FTO inhibitor; anticonvulsant
| Target | Other Oxidase/Oxygenase Compounds |
|---|---|
| CAS | 1585219-04-0 |
| Purity | 0.98 |
| Chemical Name or Material | N-[5-(4-Chlorophenyl)-3,4-dihydroxy-2-furanyl]ethanesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C12H12ClNO5S |
400
Tocris Bioscience™ Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with terminal piperidine for onward chemistry
401
Tocris Bioscience™ Adavosertib
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective Wee1 inhibitor
| Target | Checkpoint Control Kinase Inhibitors |
|---|---|
| CAS | 955365-80-7 |
| Purity | 98% |
| Chemical Name or Material | 1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3 H-pyrazolo[3,4-d]pyrimidin-3-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C27H32N8O2 |
402
Tocris Bioscience™ VH 032 amide-alkylC2-amine
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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VH 032-AlkylC2-Amine
403
Tocris Bioscience™ T 3364366
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and reversible fatty acid desaturase 1 inhibitor; orally bioavailable
| CAS | 1356354-09-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[2-[[3,4-Dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]acetamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H16F3N3O3S2 |
| Formula Weight | 443.46 |
404
R&D Systems™ GDP-Biotin-Fucose
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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405
Tocris Bioscience™ Mefloquine hydrochloride
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Cx36 and Cx50 gap channel blocker